Requirement

Raw Genetic Data, which is the next generation sequencing output, and intermediate outputs produced during the analysis of this raw data constitute large files. In addition to raw sequencing data, genetic diagnosis physicians maintain the records of their genetic diagnosis by preserving all of the formats obtained during file conversions during the analysis process, and store the results in the fastq, bam, vcf and excel formats of a single sample.

For example, only one execution (the sum of samples used in each run of the Next Generation Sequencing device) results in .fastq format raw data up to 40 GB. The size of the .bam file created during the analysis of this data can be up to 10 GB.

The total amount of genetic data held by institutions easily reaches dozens of TB levels and this total increases exponentially.

Keeping data of this size on personal computers or external drives is not practical, but also causes problems such as continuous growth of storage space, data loss and data security.

Given the current internet infrastructure, uploading files of this size directly to the cloud is a problem in itself.

Solution

It will compress the genetic data in fastq, bam, vcf, bed, excel formats and the phenodata of this data (such as gender, disease symptoms, age at which the disease occurs) with a special algorithm, and then encrypt them to the cloud environment with the password determined by the user. to install. The application that allows the user to view, download and decrypt the files when he wants to access them again: GENE2STORE.